What Are GLP-1 Agonists?

GLP-1 agonists are a class of drugs primarily used for managing type 2 diabetes that have also proven to be helpful for supporting weight loss. These medications work by mimicking the actions of the glucagon-like peptide-1 hormone, aiding in blood sugar regulation and promoting a feeling of fullness.

Woman injecting a GLP-1 into her stomach
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How Do GLP-1 Agonists Help You Lose Weight?

GLP-1 agonists assist in weight loss by helping control overall calorie consumption. This is achieved in two key ways. Firstly, they slow gastric emptying, keeping food in the stomach longer and extending post-meal fullness. This reduces the urge to eat frequently or avoid excessive overeating.

Secondly, these medications positively impact the brain’s satiety centers, responsible for signaling when we are full. By stimulating these centers, GLP-1 agonists promote satisfaction with smaller food portions, further supporting reduced total calorie intake. Together, these enable GLP-1 agonists to be helpful in weight loss strategies.

 

Are You a Good Candidate for GLP-1 Agonists for Weight Loss?

While GLP-1 agonists work well for controlling blood sugar and helping with weight loss, it’s important to remember that they aren’t suitable for everyone, including pregnant individuals or those with certain pre-existing health conditions, like a history of pancreatitis. GLPL-1 agonists are typically prescribed only for those patients with a BMI greater than 30.

It is critical to consult a healthcare professional to understand the benefits and risks of starting a GLP-1 agonist and determine if it fits you.

 

Frequently Asked Questions

Q: Can I get GLP-1 agonists over the counter?

A: They’re only available by prescription due to their specific medical uses and potential side effects, which require medical supervision.

Q: How quickly do you lose weight on GLP-1 agonists?

A: Many patients observe changes occurring in a few weeks. However, significant results generally take several months. The exact timeline for weight loss will vary depending on diet, exercise and compliance.

Q: What side effects are associated with GLP-1 agonists?

A: Common side effects include nausea, vomiting, diarrhea, constipation and decreased appetite, with possible injection site reactions. Serious side effects like pancreatitis or kidney issues are less common.

Q: Can GLP-1 agonists be combined with other weight-loss medications?

A: Yes, but only under medical supervision. The safety and effectiveness of combining medications will depend on a patient’s individual health conditions and the specific medications involved.

Q: Do GLP-1 agonists help with conditions other than weight loss?

A: GLP-1 agonists were initially developed to manage type 2 diabetes, and some studies have shown evidence that they might have positive effects on cardiovascular health. Please consult with a medical professional to determine if they are appropriate for your condition.